Check out this random public study from the database!

Wilson_CKD

Study of mice predisposed to chronic kidney disease. Samples are a time series of fecal pellets during development of the disease, with and without treatment. A strong relationship between intestinal inflammation and adverse outcomes exists in chronic kidney disease (CKD). In CKD animal, colon wall inflammation is associated with breakdown of the epithelial tight junction barrier leaky gut and translocation of bacterial DNA and endotoxin into the bloodstream. The translocation of these toxins from the leaky gut into the bloodstream further promotes systemic inflammation, adverse cardiovascular outcomes and CKD progression.

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